Duloxetine API Anti-Depressant and Analgesic 136434-34-9 Duloxetine Hydrochloride
|FOB Price:||US $1 / kg|
|Min. Order:||1 kg|
|Min. Order||FOB Price|
|1 kg||US $1/ kg|
|Payment Terms:||L/C, T/T, Western Union|
- Model NO.: 136434-34-9
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- CAS: 136434-34-9
- MW: 218.63
- Specification: USP34; EP7.0; BP2010; CP2010
- Powder: Yes
- Certification: USP
- State: Powder
- Name: Metoclopramide Hydrochloride
- Mf: C6h13clf2n2o2
- Trademark: Dahua
- Origin: Wuhan
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Anti-depressant And Analgesic 136434-34-9 Duloxetine hydrochloride
Product Name:Duloxetine hydrochloride
Synonyms:(S)-DULOXETINE HYDROCHLORIDE;LY-248686;DULOXETINE HCL;DULOXETINE HYDROCHLORIDE;N-methyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride;(RS)Duloxetine HCl;(+)-(S)-N-Methyl-g-(1-naphthyloxy)-2-thiophenepropylamine;(gS)-N-Methyl-g-(1-naphthalenyloxy)-2-thiophenepropanamine
Chemical Properties:White Crystalline Solid
Usage:Labelled Duloxetine, which is used as an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Current lot is 97% d7 with no d0, d1 or d2
Usage:An antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.
Usage:leucotriene antagonist, antiasthmatic
Usage:anti-depressant, analgesic for osteoarthiritis and musculoskeletal pain
Usage:solubility H2O: soluble5 mg/mL (clear solution, warmed)
.1Duloxetine, sold under the brand name Cymbalta among others, is a serotonin-norepinephrine reuptake inhibitor (SNRI) created by Eli Lilly. It is mostly prescribed for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain.
2.Duloxetine failed to receive US approval for stress urinary incontinence amid concerns over liver toxicity and suicidal events; however, it was approved for this indication in the UK, where it is recommended as an add-on medication in stress urinary incontinence instead of surgery.
|Items of analysis||Specification||Results|
|Description||White or off- white crystalline powder||White crystalline powder|
|Loss on drying (%)||Not more than 0.5%||0.2%|
|Assay by HPLC(A%)||Not less than 98.0%||99.5%|
1.The main uses of duloxetine are in major depressive disorder, generalized anxiety disorder, urinary incontinence, neuropathic pain, chronic musculoskeletal pain, and fibromyalgia.
2.Duloxetine is recommended as a first line agent for the treatment of chemotherapy-induced neuropathy by the American Society for Clinical Oncology, as a first-line therapy for fibromyalgia in the presence of mood disorders by the German Interdisciplinary Association for Pain therapy, as a Grade B recommendation for the treatment of diabetic neuropathy by the American Association for Neurology and as a level A recommendation in certain neuropathic states by the European Federation of Neurological Societies.
3.A 2014 Cochrane review concluded that duloxetine is beneficial in the treatment of diabetic neuropathy and fibromyalgia but that more comparative studies with other medicines are needed. The medical journal Prescrire (based in France) concluded that duloxetine is no better than other available agents and has a greater risk of side effects. Thus they recommend against its general use.
Wuhan Dahua Weiye Pharmaceutical Chemical Co.,Ltd, a professional raw powder factory in China for over 10 years, all powders are factory directly supplying. Imaginechem can help our worldwide customers shorten the time and lower the cost of drug and medical device Research and Development through cost-effecitve and efficient outsourcing solutions.
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