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Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.

Duloxetine, Duloxetine Hydrochloride, Duloxetine HCl manufacturer / supplier in China, offering Duloxetine API Anti-Depressant and Analgesic 136434-34-9 Duloxetine Hydrochloride, Reduce Blood Press Losartan Potassium for Hypertension Treatment (CAS 124750-99-8), Injectable Anabolic Steroids Supplements Trenbolone Acetate and so on.

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Supplier Homepage Product Pharmaceutical raw materials Duloxetine API Anti-Depressant and Analgesic 136434-34-9 Duloxetine Hydrochloride

Duloxetine API Anti-Depressant and Analgesic 136434-34-9 Duloxetine Hydrochloride

FOB Price: US $1 / kg
Min. Order: 1 kg
Min. Order FOB Price
1 kg US $1/ kg
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Production Capacity: 5000000kg
Transport Package: 25kg/Drum
Payment Terms: L/C, T/T, Western Union

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Basic Info
  • Model NO.: 136434-34-9
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • CAS: 136434-34-9
  • MW: 218.63
  • Specification: USP34; EP7.0; BP2010; CP2010
  • Powder: Yes
  • Certification: USP
  • State: Powder
  • Name: Metoclopramide Hydrochloride
  • Mf: C6h13clf2n2o2
  • Trademark: Dahua
  • Origin: Wuhan
Product Description

Dear friend, thanks for visiting our website. This is Luna, I can check email and reply you at any time. Any items that you are interested in, pls feel free to contact me, I will reply you at the first time, and I will value every chance to be your reliable partner.

Anti-depressant And Analgesic 136434-34-9 Duloxetine hydrochloride 
Product Name:Duloxetine hydrochloride
Synonyms:(S)-DULOXETINE HYDROCHLORIDE;LY-248686;DULOXETINE HCL;DULOXETINE HYDROCHLORIDE;N-methyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride;(RS)Duloxetine HCl;(+)-(S)-N-Methyl-g-(1-naphthyloxy)-2-thiophenepropylamine;(gS)-N-Methyl-g-(1-naphthalenyloxy)-2-thiophenepropanamine
CAS:136434-34-9
MF:C18H20ClNOS
MW:333.88
EINECS:200-659-6
Chemical Properties:White Crystalline Solid
Usage:Labelled Duloxetine, which is used as an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Current lot is 97% d7 with no d0, d1 or d2
Usage:An antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.
Usage:leucotriene antagonist, antiasthmatic
Usage:anti-depressant, analgesic for osteoarthiritis and musculoskeletal pain
Usage:solubility H2O: soluble5 mg/mL (clear solution, warmed)


Duloxetine hydrochloride-----Description

.1Duloxetine, sold under the brand name Cymbalta among others, is a serotonin-norepinephrine reuptake inhibitor (SNRI) created by Eli Lilly. It is mostly prescribed for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain.

2.Duloxetine failed to receive US approval for stress urinary incontinence amid concerns over liver toxicity and suicidal events; however, it was approved for this indication in the UK, where it is recommended as an add-on medication in stress urinary incontinence instead of surgery.


COA
 
Items of analysisSpecificationResults
DescriptionWhite or off- white crystalline powderWhite crystalline powder
Loss on drying (%)Not more than 0.5%0.2%
Melting Point160.0~165.0ºC162.7~163.3
Specific Rotation+115.0~+125.0°+117.8°
Heavy metals≤0.001%<0.001%
Purity(HPLC)Single impurity≤0.5%0.2%
Assay by HPLC(A%) Not less than 98.0%99.5%
ConclusionQualified


Duloxetine hydrochloride-----Application

1.The main uses of duloxetine are in major depressive disorder, generalized anxiety disorder, urinary incontinence, neuropathic pain, chronic musculoskeletal pain, and fibromyalgia.

2.Duloxetine is recommended as a first line agent for the treatment of chemotherapy-induced neuropathy by the American Society for Clinical Oncology, as a first-line therapy for fibromyalgia in the presence of mood disorders by the German Interdisciplinary Association for Pain therapy, as a Grade B recommendation for the treatment of diabetic neuropathy by the American Association for Neurology and as a level A recommendation in certain neuropathic states by the European Federation of Neurological Societies.

3.A 2014 Cochrane review concluded that duloxetine is beneficial in the treatment of diabetic neuropathy and fibromyalgia but that more comparative studies with other medicines are needed. The medical journal Prescrire (based in France) concluded that duloxetine is no better than other available agents and has a greater risk of side effects. Thus they recommend against its general use.
 

About us: 
Wuhan Dahua Weiye Pharmaceutical Chemical Co.,Ltd,  a professional raw powder factory in China for over 10 years, all powders are factory directly supplying. Imaginechem can help our worldwide customers shorten the time and lower the cost of drug and medical device Research and Development through cost-effecitve and efficient outsourcing solutions.
 

Packaging & Delivery:
1. Shipping by express (FedEx, UPS, DHL, EMS), by air; By ship.
2. Shipment will be arranged within 24 hours after receiving the payment;
3. Pictures of the package will be sent to you then along with the tracking number; Super discreet packaging, to ensure safe delivery, 99% successful delivery rate is ensured. Delivery time: All of the orders will be packed within 24 hours after we get the payment usually it takes about3~5work days for you to get the parcel. Payment method: Bank wire, Western union, Moneygram
4. How to proceed order: First: Please let me know the itmes you are looking for, quantity, and the destination country. Second: You confirm all details, and offer us purchasing order; Third: We send the detail price of our product and offer the suitable shipping method for reference. Forth: You confirm the order and pay money 100% in advance and send us the detail address. Fifth: We arrange the shipment according to your requirements. Sixth: We offer after-sales service after you receive parcel
 

If you need this or you are interest in this kind of products, you are free to send me email or call me directly, we can talk more about the details of the products.
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Luna (^_^)
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