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Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.

Tetracaine Hcltetracaine, Tetracaine HCl, Tetracaine Hydrochloride manufacturer / supplier in China, offering Anesthetic Tetracaine Hydrochloride Tetracaine HCl Tetracaine (CAS: 136-47-0), High Assay Pharmaceutical Raw Materials Ampicillin Sodium CAS: 69-52-3, Sell Hot Antibacterial Drug Vancomycin Hydrochloride/Vancomycin Hci 1404-93-9 and so on.

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Supplier Homepage Product Hot sell chemical Anesthetic Tetracaine Hydrochloride Tetracaine HCl Tetracaine (CAS: 136-47-0)

Anesthetic Tetracaine Hydrochloride Tetracaine HCl Tetracaine (CAS: 136-47-0)

FOB Price: US $1 / kg
Min. Order: 25 kg
Min. Order FOB Price
25 kg US $1/ kg
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Port: Shanghai, China
Production Capacity: 5000kg/Month
Payment Terms: T/T, Western Union, Paypal, Money Gram, Bitcoin

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Basic Info
  • Model NO.: 136-47-0
  • Customized: Non-Customized
  • Suitable for: Elderly, Children, Adult
  • Purity: >99%
  • MOQ: 10gram
  • Transport Package: According to Customer′s Requirements
  • Origin: China
  • Powder: Yes
  • Certification: ISO 9001
  • State: Solid
  • MW: 300.82
  • Trademark: Dahua
  • Specification: USP/BP, EP
  • HS Code: 3001200020
Product Description

Anesthetic Tetracaine Hydrochloride Tetracaine HCl Tetracaine (CAS: 136-47-0)

Quick Details:

  • Tetracaine HCl
  • Alias: Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride;
  • 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride
  • CAS NO.: 136-47-0
  • EINECS: 205-248-5
  • MF: C15H25ClN2O2
  • MW: 300.82
  • Melting point: 149°C
  • Assay: 99%
  • Grade: Pharmaceutical Grade
  • Storage: Closed, confined and shading preservation
  • Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.

 

Description:

Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

 

Application:

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

 

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